You should pull up and remove weeds by hand as and when they appear. If it is a regular problem, you might need to reseal the paving. In extreme cases, the sub layer itself may need to be re-laid. You can use weed killer, however some paving can be discoloured by stronger weed killers.
Brampton
Brampton (population 4,627) is a tiny market town, civil parish as well as electoral ward within the City of Carlisle district of Cumbria, England, regarding 9 miles (14 kilometres) east of Carlisle as well as 2 miles (3.2 km) south of Hadrian's Wall surface. Historically part of Cumberland, it is positioned off the A69 road which bypasses it. Brampton railway station, on the Newcastle and also Carlisle Railway, is about a mile outside the community, near the district of Milton. St Martin's Church is well-known as the only church created by the Pre-Raphaelite designer Philip Webb, and also consists of among the most beautiful sets of discolored glass windows made by Sir Edward Burne-Jones, and carried out in the William Morris studio.